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Common side effects include nausea, vomiting, diarrhoea, and constipation, which often diminish over time as the body adjusts to treatment
16 Furthermore, as these models rely on immunocompromised hosts, they cannot replicate immune-related resistance mechanisms
The first step in the synthesis of GSH is the formation of -glutamyl-cysteine (GluCys) from the constituent amino acids glutamate and cysteine by the enzyme -glutamyl-cysteine synthetase (GCS, also called glutamate cysteine ligase (GCL))